New PDF release: Biopsy Interpretation: The Frozen Section

By Jerome B. Taxy, Aliya N. Husain, Anthony G. Montag

ISBN-10: 0781767792

ISBN-13: 9780781767798

This new quantity of the Biopsy Interpretation Series is a pragmatic, fantastically illustrated consultant to the technical and interpretive points of a frozen part. the focal point is on use of the frozen part in intraoperative administration of sufferers, fairly people with tumors. The authors supply pathologists a radical wisdom of the software and obstacles of a frozen part, the perfect situations for doing one, the correct ideas, and the translation and reporting of effects. The ebook gains greater than three hundred full-color gross and microscopic photographs, with discussions of differential diagnosis.

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Additional info for Biopsy Interpretation: The Frozen Section

Example text

4). 6 display an endometrial carcinoma metastatic to the ovary. The presence of dirty necrosis on both the touch preparation and the cryostat section suggests metastatic disease. 1. The features most predictive for metastatic disease and useful on frozen section are bilaterality, microscopic surface involvement, macroscopic nodular growth pattern, infiltrative invasive growth pattern, and infiltration of stroma by small glands or individual cells. Interestingly many features had no discriminatory value: gross necrosis; cribriform, villous, or solid growth pattern; goblet cells or colonic carcinoma-like appearance, and low-grade histology.

13. Meyer MS, Spanier SS, Moser M, et al. Evaluating marrow margins for resection of osteosarcoma: a modern approach. Clin Orthop Relat Res. 1999;363:170–175. 14. Mirra JM, Marder RA, Amstutz HC. The pathology of failed joint arthroplasty. Clin Orthop Relat Res. 1982;170:175–183. 15. Kanner WA, Saleh KJ, Frierson HF. Reassessment of the usefulness of frozen section analysis for hip and knee revisions. Am J Clin Pathol. 2008;130:363–368. 16. Pandey R, Drakoulakis E, Athanasou NA. An assessment of the histological criteria used to diagnose infection in hip revision arthroplasty tissues.

Apparently localized lesions are found to have other sites of involvement on staging in a quarter of cases (2). Underdiagnosis at frozen section may lead to understaging, while overdiagnosis of malignancy may result in inappropriate loss of fertility. As in all intraoperative consultations, the pathologist should know the surgeon’s treatment algorithm based on the diagnosis rendered. A careful documentation of the intactness of the ovarian capsule and examination for surface involvement should precede opening the specimen.

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Biopsy Interpretation: The Frozen Section by Jerome B. Taxy, Aliya N. Husain, Anthony G. Montag


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