By Dr. Hans Wolfgang Kölmel (auth.)
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Extra info for Atlas of Cerebrospinal Fluid Cells
Patient: male, 25 years old. CSF: 250 cellsf mm 3 , 6% eosinophils. c "Foreign body" meningitis after implantation of a Spitz-Holter drain. Patient: female, 3 years old. CSF: 600 cellsfmm 3 , 90% eosinophi/so a •• • • • 35 5. Plasma Cells Plasma cells are present only in pathologically altered CSF and develop primarily out of sessile leptomeningeal stem cells [40, 75, 100, 144], although a few may migrate from the blood into the CSF. Immature plasma cells usually have a large, centrally-located nucleus and lightblue cytoplasm, while increasingly basophilic cytoplasm is characteristic of maturing cells.
Some authors emphasize their vulnerability in vitro , but they can often be better preserved than neutrophilic granulocytes, if no more than 3 hours elapse between collection of the sample and fIxation of the cells. The normal CSF contains no eosinophils. Since they also appear rarely in the majority of infectious reactions, any increase in their number demands special attention. Eosinophils can be present in any infectious pleocytosis, but they usually constitute less than I % of the total number of cells.
Declining numher of transformed lymphocytes. Signs of monocyte mohilisation. CSF: 110 cells/mm 3 , 90 mg% protein. a c 49 zorek proposed, for example ) is not easy. Lymphoid cells can appear in all forms of infectious pleocytosis of the CSF  and occasionally appear in reaction to foreign elements, as in the case of myelography or subarachnoid hemorrhage. They are always present in the cytograms of tuberculous CSF, often in the early stage, and deserve special attention. Plate 18 Fatal tuberculous meningoencephalitis.
Atlas of Cerebrospinal Fluid Cells by Dr. Hans Wolfgang Kölmel (auth.)