By Douglas J. Martin BS, Edward G. Randles PhD, Marina Ramirez-Alvarado PhD (auth.), Morie A. Gertz, S. Vincent Rajkumar (eds.)
An updated reference in this interesting set of advanced issues, this ebook positive aspects the main complete ideas for diagnosing, classifying, imaging, treating, and dealing with amyloidosis in a number of organ platforms. important to the spectrum of practitioners from citizens to sub-specialists, this ebook is a succinct authoritative textual content written by means of leaders within the box. The authors supply guide on all kinds of amyloidosis - together with fundamental amyloidosis (AL), secondary amyloidosis (AA), and familial amyloidosis. With crucial remedy algorithms, Amyloidosis: analysis and remedy is the gold-standard for all hematologists, oncologists, and internists taking good care of sufferers with this disease.
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Extra info for Amyloidosis: Diagnosis and Treatment
Am J Cardiol. 1982;49:9–13. 69. Koyama J, Ray-Sequin PA, Falk RH. Prognostic significance of ultrasound myocardial tissue characterization in patients with cardiac amyloidosis. Circulation 2002;106: 556–61. 70. Ganau A, Devereux RB, Roman MJ, et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. J Am Coll Cardiol. 1992;19:1550–8. 71. Dubrey SW, Cha K, Anderson J, et al. The clinical features of immunoglobulin lightchain (AL) amyloidosis with heart involvement.
Amyloid cardiomyopathy: characterization by a distinctive voltage/mass relation. Am J Cardiol. 1982;49:9–13. 69. Koyama J, Ray-Sequin PA, Falk RH. Prognostic significance of ultrasound myocardial tissue characterization in patients with cardiac amyloidosis. Circulation 2002;106: 556–61. 70. Ganau A, Devereux RB, Roman MJ, et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. J Am Coll Cardiol. 1992;19:1550–8. 71. Dubrey SW, Cha K, Anderson J, et al.
They are at the most helpful in screening, and positive results should always be confirmed by more specific methods . Congo red still reigns as the “king of dyes” in the diagnosis of amyloid . The old Bennhold technique has been significantly modified by Puchtler and provides a better specificity . Others used a slightly modified method by Romhányi . Moreover, following Congo red staining, amyloid gives an “apple-green birefringence” under polarization which is specific for amyloid and definitely distinguishes amyloid from collagen.
Amyloidosis: Diagnosis and Treatment by Douglas J. Martin BS, Edward G. Randles PhD, Marina Ramirez-Alvarado PhD (auth.), Morie A. Gertz, S. Vincent Rajkumar (eds.)