Advances in Management and Treatment of Depression by Michael E Thase MD, John Potokar, Michael E. Thase PDF

By Michael E Thase MD, John Potokar, Michael E. Thase

ISBN-10: 0203002881

ISBN-13: 9780203002889

ISBN-10: 1841841536

ISBN-13: 9781841841533

Verified specialists current all points of melancholy during this easy-to-read guide, with an emphasis on new advancements within the remedy of melancholy. all of them aspect the most recent proof of their area of expertise parts. The textual content specializes in useful concerns, so it is helping the pro transition from evidence-based medication to day by day scientific perform. The authors tackle 5 of the commonest concerns in melancholy, together with matters voiced often via their sufferers and questions from different practitioners. Advances in administration and therapy of melancholy is focused at training psychiatrists and basic practitioners.

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The loss of hippocampal volume appears to be correlated with the total lifetime illness duration and may persist for up to decades after the depressive episodes have resolved (Sheline et al, 1999; Bremner et al, 2000). N-acetylaspartate (NAA) is regarded as a marker of neuronal viability and function and can be assessed via magnetic resonance spectroscopy (MRS). Frye and others (Frye et al, 2000; Winsberg et al, 2000) found decreased NAA levels in the hippocampus and the dorsolateral prefrontal cortex of bipolar subjects.

Are individuals with depression at increased risk of having other comorbid psychiatric illnesses? Comorbidity of depressive disorders with other psychiatric disorders seems to be the rule rather than the exception, especially when comorbidity is considered in terms of lifetime co-occurrence of disorders. Lifetime comorbidity rates are particularly high in individuals with bipolar illness. Both bipolar and unipolar depressive illnesses show particularly large associations with anxiety and substance-use disorders.

4 (data from Weissman et al, 1996). The figure presents odds ratios for the two substance-use and the two anxiety disorder diagnoses that were the most frequently comorbid in these studies. Thus, in the US (based on the ECA study), individuals with a history of major depression were twice as likely to also meet lifetime criteria for alcohol abuse and/or Depression: Epidemiology and risk factors 15 dependence. They were over four times as likely to meet criteria for lifetime drug abuse/dependence, over five times as likely to meet criteria for obsessive-compulsive disorder, and over nine times more likely to meet criteria for panic disorder.

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Advances in Management and Treatment of Depression by Michael E Thase MD, John Potokar, Michael E. Thase

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